麻酔ガストロスコーピーの小児における低酸素症の発生率に対する経鼻加湿呼吸器交換の効果: ランダム化制御試験
He Geng1, Cuicui Yao2, Lixin Wu2
1Department of Anaesthesiology, Shenzhen Children's Hospital of China Medical University, Shenzhen, China.
BMC pediatrics
|August 31, 2025
まとめ
鼻経湿化呼吸器交換は,小児鎮静ガストロスコピーの際にヒポキシミアの発生率を著しく減少させた. この新しい換気法は酸素供給を改善し,小児の呼吸に関する有害事象を減少させました.
科学分野:
- 小児麻酔科
- 呼吸器のケア
- 胃腸内科
背景:
- トランスナザル加湿型急速吸気換気器 (THRRIVE) は,高流量,加熱,加湿ガスを供給します.
- 小児麻酔ガストロスコピーにおけるその使用は,まだ十分に調査されていない.
研究 の 目的:
- 小児の鎮静ガストロスコピーにおける低酸素症の軽減におけるTHRIVEの有効性を評価する.
- THRIVEと標準的な鼻カヌラ酸素治療を比較する
主な方法:
- 予期的なランダム化臨床試験で,静止薬による胃鏡検査を受けた120人の子ども (6~12歳) が対象となった.
- 参加者は無作為に THRIVE または鼻カヌーラから酸素を受け取った.
- 主要評価は低酸素症の発生率であり,次要評価は酸素飽和度,低酸素症の持続時間,および有害事象であった.
主要な成果:
- 鼻カヌーラ (P<0. 01) 投与の28. 3%に対して,THRIVEを投与した子供の8. 3%で低酸素症が発生した.
- THRIVEグループは,ヒポキシミアの持続期間が著しく短く,介入率が低く,有害な呼吸器系の合併症が少なくなった.
- THRIVE群では,内視鏡検査の満足度が著しく高かった (88. 3% vs 68. 3%).
結論:
- THRIVEは,小児の鎮静ガストロスコピーにおける酸素供給を効果的に促進し,低酸素症の発生率を減少させます.
- この換気戦略は,内視鏡手術を受ける小児患者の安全性と快適性を向上させます.
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