Xin Tao1, Xiaoxia Yang1

  • 1Department of Infectious Disease, Heping Hospital, Affiliated to Changzhi Medical College, Changzhi, Shanxi Province, China.

PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) は肝細胞癌 (HCC) の治療に有望だが,耐性がある. このレビューでは,ICI耐性メカニズムとHCC患者の治療結果を改善するための新しい治療法を調査します.

関連する概念動画

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K