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Updated: May 2, 2026

Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS
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Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry UPLC-MS

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非標的型NMR代謝の潜在的な細胞代謝物の自動識別

Jiashang Chen1, Angela Rao1, Rajshree Ghosh Biswas1

  • 1Departments of Radiology and Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

NMR in biomedicine
|September 1, 2025
PubMed
まとめ

新しい Python プログラムである ROIAL-NMR は,核磁気共振 (NMR) スペクトロスコーピーを用いて複雑な生物サンプルから代謝物を特定するのに役立ちます. 肺がん患者と アルツハイマー病やそれに関連する認知症を 区別することに成功しました

キーワード:
自動メタボリート識別核磁共振スペクトロスコーピーパイソンプログラム

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Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
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