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Updated: Sep 9, 2025

Using Nicotine in a Silica-Exposed Mouse Model to Promote Lung Epithelial-Mesenchymal Transition
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SiO2誘発性肺線維症におけるマクロファージ低酸素の役割の概要

Yuan-Yuan Fu1,2, Yan-Rui Liu1,2, Hui-Jie Hu2

  • 1School of Public Health, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.

Journal of applied toxicology : JAT
|September 1, 2025
PubMed
まとめ

シリコシスはシリカ (SiO2) 粒子を吸い込むことで発生し,アルベオラマクロファージの低酸素症と肺線維症を引き起こします. この低酸素症をターゲットにすることで この職業性肺疾患の 治療戦略が生まれます

キーワード:
SiO2 についてアルベオラマクロファージの低酸素肺繊維症シリコシス

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