高齢者の大麻使用と認知: 予備的なパフォーマンスベースの神経心理学的検査結果と将来の研究方向
Kyler Mulhauser1,2, Daniel Sullivan1, Jessica L Bair3
1Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Journal of the International Neuropsychological Society : JINS
|September 1, 2025
まとめ
最近の大麻を使用した高齢者は,全体的な認知機能に影響を与えませんでした. しかし,大麻使用障害の症状が増加すると,この集団の記憶能力が低下することが判明しました.
科学分野:
- 神経科学
- ゲロントロジー
- 心理学
背景:
- 認知の老化は高齢者の大きな懸念です
- 大麻の使用は高齢者の間で増加しています.
- 大麻が認知能力に及ぼす影響は十分に理解されていません.
研究 の 目的:
- 最近の大麻使用に基づく認知症連続体における高齢者 (65歳以上) の神経心理学的機能の違いを評価する.
- 大麻関連の問題の重症度と認知的結果との関連を調査する.
主な方法:
- 観察コホートから540人の高齢者の分析
- 最近 (過去6ヶ月間) の大麻使用に関するアンケート
- 徹底した神経心理検査
- 多変数,単変数,および傾向スコアマッチング (PSM) の分析が採用された.
主要な成果:
- 約11%の参加者が最近の大麻使用を報告した.
- 最近の大麻使用者は,5つの認知領域で非使用者と同様のパフォーマンスを示しています.
- 最近の大麻使用者では,大麻使用障害 (CUD) のリスクが高まり,記憶力の低下と関連していました.
結論:
- 認知機能低下を含む高齢者では,低頻度の大麻使用が認知的によく許容されるようです.
- 大麻使用障害の症状は,高齢者の記憶に悪影響を及ぼす可能性があります.
- 認知に影響を与える大麻使用パターン,個々の要因,および臨床的現象に関するさらなる研究が必要である.
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