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抗BAFF mAb治療は,全身性ループス・エリーテマトス患者におけるレギュレータのB細胞を増加させ,エフェクタのB細胞を減少させる

Takashi Matsushita1

  • 1Department of Dermatology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.

The Journal of dermatology
|September 1, 2025
PubMed
まとめ

No abstract available in PubMed .

キーワード:
アンチBAFF mAbエフェクターB細胞規制Bセル全身性赤血性狼

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B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
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