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NLRC4 p.Val342Ala: IL-18の洞察について

Daigo Kato1, Yoshitake Sato1, Kanako Mitsunaga1

  • 1Department of Allergy and Rheumatology, Chiba Children's Hospital, Chiba City, Chiba, Japan.

Pediatrics international : official journal of the Japan Pediatric Society
|September 1, 2025
PubMed
まとめ

No abstract available in PubMed .

キーワード:
NLRC4 についてバール342Ala幼児の自己炎症性腸炎インタールイキン‐18マクロファージ活性化症候群

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Introduction
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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