高齢者における鼻がんに対する放射線治療の治療結果:観察的,遡及的,単一センター研究
Dang Nguyen Van1,2, Duc Dinh1, Hang Nguyen Thi1
1VietNam National Cancer Hospital - K Hospital, Hanoi, Vietnam.
Science progress
|September 1, 2025
まとめ
鼻がん (NPC) の高齢患者は,若年層と比較して,放射線治療で良好な結果を示しています. 臨床段階,70歳以上の年齢,および併発症は生存の重要な予測因子です.
科学分野:
- 腫瘍学
- 放射線腫瘍学
- 高齢者医療
背景:
- 鼻がん (NPC) の発生率は高齢者集団で増加しています.
- 高齢のNPC患者に対する最適な治療戦略については,さらなる調査が必要である.
研究 の 目的:
- 治療の成功を評価し,最終的な放射線治療を受けるNPCの高齢患者 (≥60歳) の予後要因を特定する.
- この特定の集団における生存率と治療耐性を分析する.
主な方法:
- 組織学的に確認された不分化鼻がん (UCNT) の125人の高齢患者の遡及分析.
- 2018年1月から2023年12月まで収集されたデータ,臨床段階,併発症,治療結果を含む.
- 多変量分析を用いて予後変数を決定した.
主要な成果:
- このコホート (平均年齢65. 9歳) の全生存率はそれぞれ93%と69%であった.
- 5年無病生存率は72%でした.
- 臨床段階と併発症は全生存期に有意な影響を及ぼした (P < .05).
結論:
- 高齢のNPC患者は,一般の患者と比較可能な臨床的特徴と生存結果を示しています.
- 臨床段階,70歳以上の年齢,および併発症は生存の独立した予測因子です.
- 高齢のNPC患者の治療を最適化するために,多学科的な治療方法が不可欠です.
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