アイルランドの初等医療における鎮痛薬の処方と高リスクの処方パターン 2014-2022-A Repeated Cross-Sectional Study
Molly Mattsson1, Ahmed Hassan Ali1, Fiona Boland2
1School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
European journal of pain (London, England)
|September 1, 2025
まとめ
アイルランドにおける鎮痛薬の使用は,主に非ステロイド性抗炎症薬 (NSAID) の処方量の減少により,全体的に減少した. しかし,高リスクの処方パターンは依然として存在し,介入と専門的な支援の必要性を示しています.
科学分野:
- 薬剤監視と医薬品の安全性
- 主要治療薬
- 医療サービス研究
背景:
- 痛みの管理は公衆衛生上の大きな課題であり 鎮痛剤は効果があるものの リスクも伴います
- 非ステロイド性抗炎症薬 (NSAIDs) とオピオイドは副作用と依存性の可能性があるため,高リスクの鎮痛剤です.
- 鎮痛剤の処方に関する傾向を理解することは 患者の安全と医療資源の割り当てを最適化するために不可欠です
研究 の 目的:
- 2014年から2022年までのアイルランドのプライマリケアにおける鎮痛剤の処方パターンの変化を分析する.
- 特定の鎮痛薬のクラスと高リスクの処方行動におけるシフトを特定する.
- 痛みの管理における薬剤の安全性の改善のための戦略を提示する.
主な方法:
- アイルランドの一般医療サービス (GMS) の月間データを用いて,プライマリケアで処方され,配給される医薬品について調べました.
- 量化された年間流行,開始,中止,および鎮痛剤の慢性的な使用.
- スコットランドのポリファーマシーガイドラインの基準に基づいて,高リスクの処方箋を評価した.
主要な成果:
- 鎮痛薬の総流行率は2014年の48.3%から2022年の46.3%にわずかに減少した.
- 非ステロイド性抗炎症薬 (NSAID) の使用は,研究期間中に29. 4%から25. 0%に大幅に減少しました.
- 他の鎮痛剤の流行は増加し,ガバペンチノイドとアミトリプチリンは2022年に調整された確率で高かった. NSAIDと抗凝固剤などの高リスクの処方薬は増加しました.
結論:
- アイルランドでは全般的な鎮痛薬の使用が減少しており,これは主に全身性NSAIDの処方量の減少に起因している.
- 他の鎮痛剤の増加は,特に高齢化の人口の変化に起因する可能性があります.
- 高リスクの処方と非薬学的な疼痛管理サービスを強化する介入が推奨されています.
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