関連する実験動画

Updated: Sep 9, 2025

"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM
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"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM

Published on: August 26, 2016

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物理的な閉じ込めとファゴサイトの吸収は,持続的な細胞移動を誘導する

Summer G Paulson1,2, Sophia Liu1,2, Jeremy D Rotty1

  • 1Uniformed Services University of the Health Sciences, Department of Biochemistry, Bethesda, MD, 20814, USA.

Biology open
|September 1, 2025
PubMed
まとめ

物理的な閉じ込めは,BV2マイクログリアのような細胞のファゴシトーシスを著しく強化し,強力な駆動力として作用します. この効果にはArp2/3複合体とミオシンIIが関与し,細胞の移動と免疫反応に影響する.

キーワード:
アクチンArp2/3 コンプレックス限られた運動能力フィブロネクチンミクログリアミオシンファゴサイトーシス

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