舌が腫れた女性: 言語のみに影響するANCA陰性局部化エオシノフィルの豊富な粒状炎症の希少な症例
Fabio Munzinger1, Luca Giudici2, Michael B Soyka3
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital and University of Zurich, Zurich, Switzerland. Fabio.munzinger@usz.ch.
HNO
|September 1, 2025
まとめ
エオシノフィル・グラヌロマトーシスとポリヤングライト (EGPA) はめったに舌に影響しない. このケースは,この珍しいANCA関連血管炎の局所的なプレゼンテーションと治療の課題を強調しています.
科学分野:
- リウマトロジ
- 病理学について
- 耳鼻喉科
背景:
- ANCAに関連した血管炎の一種である多管炎 (EGPA) によるエオシノフィル性粒球症は,一般的に鼻腔,肺,心臓に影響します.
- 鼻腔と内耳の関わりは頻繁ですが,他の頭と首の症状はまれに記録されています.
研究 の 目的:
- エオシノフィールに富んだ舌の粒状炎症のみを呈する EGPA の単一の症例を報告する.
- EGPAの局所的なプレゼンテーションによって引き起こされる診断と治療の課題について議論する.
主な方法:
- 舌の組織を本体病理学的に調べる
- EGPAの臨床表現と診断基準のレビュー (1992 チャペルヒルと2022 ACR/EULAR).
主要な成果:
- 舌の孤立したエオシノフィルの粒状炎症を呈した若い女性.
- プレゼンテーションは1992年の分類で局所化されたEGPAを提案したが,2022年の基準を完全に満たさなかった.
- この局所的な舌の症状の治療は困難であった.
結論:
- EGPAは,孤立した舌の関わりなど,異常な局所的形態で現れます.
- このケースは,非典型的なEGPAプレゼンテーションの現在の分類基準の限界を強調しています.
- 局所的なEGPAの管理の難しさは,適応した治療戦略の必要性を強調しています.
関連する概念動画
01:01Tongue
1.5K
The human tongue is a fascinating and complex organ, responsible for various essential functions such as swallowing, speech, and taste. It is also subject to various conditions and diseases. In this article, we delve into the anatomy of the tongue, its roles, and some common conditions that can affect it.
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
1.5K
01:26Assessment of the Mouth
401
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
401
01:23Chronic Pharyngitis
4.8K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
4.8K
01:30Tonsillitis I: Introduction
538
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
538
01:25Endocarditis II: Clinical Features of Infective Endocarditis
25
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
25
01:30Acute Pharyngitis
1.5K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
1.5K