手術後の喉癌患者の腸内栄養不耐症の改善に対する自己調製の食事療法による効果:ランダム化比較試験
Mengxuan Huang1, Jun Cao1, Jingtao Jiang1
1Department of Nutrition, EYE & ENT Hospital of Fudan University, Shanghai, 200031, China.
まとめ
臓がん患者の腸内栄養不耐症 (EFI) を減少させた. この介入により,手術後の栄養状態と腸内栄養への耐性が改善されました.
科学分野:
- 腫瘍学
- 胃腸内科
- 統合医療
背景:
- 腸内栄養不耐症 (EFI) は喉頭がん手術後の頻繁な合併症である.
- 伝統的な中国医学 (TCM) の食事療法は,胃腸機能と栄養耐性を向上させるのに有望である.
- この研究では,EFI管理のための新しいTCMの食事配列を調査した.
研究 の 目的:
- 自作のTCMダイエット療法のEFI改善の有効性を評価する.
- 喉頭がん患者におけるEFIの管理におけるこのTCMの役割を探求する.
- 腸内栄養耐性と術後の栄養状態への影響を評価する.
主な方法:
- 80人の喉癌患者を対象に ランダム化比較試験を行いました
- 介入グループは標準的な腸内栄養と25g/dayのTCMの栄養分を摂取した.
- 対照群は標準的な腸内栄養のみを受けた.
- 主なアウトカムには,EFIの発生率,栄養注入率,最初の排便までの時間が含まれていました.
- 二次的なアウトカムには,血清の総タンパク質とプレアルブミン濃度が測定された.
主要な成果:
- 介入グループではEFIの発生率が有意に低かった (50. 0% vs 71. 4%,P=0. 049).
- 腸内栄養注入率 (81. 24%対73. 77%,P=0. 009) と最初の排便までの時間 (82. 34h対101. 51h,P=0. 037) がより高いことが観察されました.
- 手術後の第7日までに全血清タンパク質とプレアルブミン濃度の改善が観察された (P=0. 040とP=0. 012).
結論:
- TCMベースの食品グレードの食事療法は,喉頭がん患者のEFI発生率を効果的に減少させました.
- 腸内栄養に対する耐性を高め 術後の栄養状態も改善した.
- この食事療法は,EFIの管理のための有望な補助療法です.
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