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Updated: Sep 9, 2025

Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke
09:45

Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke

Published on: March 22, 2016

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CaMKIIのジャヌス顔:記憶の統合からアルツハイマー病における神経毒性スイッチ

Luhong Tang1, Feng Liu2, Xuefei Sun3

  • 1Department of Clinical Pharmacology, School of Pharmacy, China Medical University, Shenyang, 110122, China.

Archives of toxicology
|September 1, 2025
PubMed
まとめ

アミロイドプラークではなく,異常なカルシウム (Ca2+) 信号がアルツハイマー病 (AD) を引き起こします. この研究は,ADの病原化と記憶障害におけるCa2+/CaM-CaMKII経路の役割を明らかにし,新しい治療標的を提供している.

キーワード:
アルツハイマー病Ca2+/CaM-CaMKIIカルシウムジホメオスタシス学習と記憶機能シナプスの可塑性

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Published on: March 16, 2016

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Modified Roller Tube Method for Precisely Localized and Repetitive Intermittent Imaging During Long-term Culture of Brain Slices in an Enclosed System09:52

Modified Roller Tube Method for Precisely Localized and Repetitive Intermittent Imaging During Long-term Culture of Brain Slices in an Enclosed System

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