自閉症児の反応抑制は,若い成人期における精神病症状を予測する - 8年間の追跡調査結果
Tim Ziermans1, Britt Kok2, Sophie van Rijn3,4
1Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands. T.b.ziermans@uva.nl.
Journal of autism and developmental disorders
|September 1, 2025
まとめ
自閉症スペクトル症候群 (ASC) の若い成人は,高いポジティブな精神病症状を示さない. 自閉症の若者における後のポジティブな症状を予測し,潜在的なリスクマーカーを示唆します.
科学分野:
- 神経発達障害
- 精神病学について
- 認知神経科学
背景:
- 軽微なポジティブな症状は 非自閉症の若者の精神病の重要な脆弱性マーカーです
- 実行機能と社会的認知の欠陥が これらの症状の発生に 関わっている.
- 自閉症スペクトル症候群 (ASC) の精神病的な症状とその認知的前駆者を理解することは極めて重要です.
研究 の 目的:
- ASCの若い成人の精神症状の有無を評価する.
- これらの症状の潜在的認知の前兆を特定する.
- ASCにおける幼少期から若年期までの精神病症状の長期的安定性を調べる
主な方法:
- 30人のASCの若い成人の精神症状を評価し,典型的な比較グループ (TC) と比較した.
- 安定性を評価するために,現在の症状スコアと遡及的な子供時代スコア (Mage=12. 1) を比較した.
- 幼児期の認知マーカーが 青年期におけるポジティブな症状を 予測できるかどうかを調べました
主要な成果:
- ASCの若い成人はTCよりも多くのネガティブな症状を示しましたが,ポジティブまたは無秩序な症状には大きな違いはありませんでした.
- ポジティブとネガティブな症状は時間とともに安定し,混乱した症状は減少した.
- 幼児期における反応抑制の精度は,若い成人期におけるポジティブな症状を有意に予測した.
結論:
- 予想に反して,ASCの若い成人の場合,正の精神症状は増加していません.
- 精神病の症状は,ASCの子供期から若い成人期まで,一般的に安定しており,個人的には顕著な変化がある.
- 自閉症の若い成人のポジティブな症状の潜在的なリスクマーカーとして出現し,さらなる研究が必要です.
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