米国における全国的な電子医療記録データセットにおける女性における高血圧と多囊性卵巣症候群

Siran He¹, Omoye Imoisili², Lyudmyla Kompaniyets³

¹Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. siranhe@gmail.com.

Maternal and child health journal

|September 1, 2025

まとめ

多囊性卵巣症候群 (PCOS) の女性は高血圧率が著しく高い. PCOS患者の早期の血圧スクリーニングは,心血管疾患の予防に不可欠です.

科学分野:

心臓病科
内分泌学
生殖健康

背景:

多囊性卵巣症候群 (PCOS) と高血圧は,生殖年齢の女性の重要な心血管疾患のリスク因子です.
電子医療記録 (EHR) は,病気の流行と関連性を研究するための貴重なデータを提供します.

研究の目的:

EHRベースのPCOSのフェノタイプを構築する.
EHRデータを用いて,米国でのPCOSの流行を決定する.
PCOSと高血圧の関連性を調べる

主な方法:

2022年のIQVIA 病院用電子医療記録 (AEMR) - 米国データを活用した横断的な研究.
PCOSのフェノタイプと報告された流行.
評価された高血圧の流行とコントロールは,PCOS状態によって層分かれています.
高血圧と対照群の計算された調整された罹患率 (aPR),年齢,人種,BMIの調整.

主要な成果:

対象となった女性は1,301,425人 (平均年齢31.5歳).
PCOSの罹患率は2. 1%で,肥満のクラス3では6. 7%に上昇した.
PCOSの女性は高血圧の罹患率が50%高かった (aPR 1. 50),コントロール率がわずかに高かった (aPR 1. 14).

結論:

PCOS の女性では,PCOS の女性と比較して高血圧の罹患率がかなり高い.
観察されたPCOSの罹患率は,以前の全体的な推定値より低かった.
PCOS患者のためのガイドラインに沿った定期的な血圧スクリーニングは,長期的な心血管リスクを軽減することができます.

キーワード:

心血管疾患電子医療記録高血圧多囊性卵巣症候群女性の健康

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