関連する実験動画

Updated: Sep 9, 2025

Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins
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Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins

Published on: May 22, 2017

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サンゴのアンソゾアンの特異的なオプシンは,スペクトル調節のために新しい塩素対陽子を使用する

Yusuke Sakai1, Saumik Sen2,3, Tomohiro Sugihara1

  • 1Department of Biology, Graduate School of Science, Osaka Metropolitan University, Sumiyoshi ku, Osaka, Japan.

eLife
|September 1, 2025
PubMed
まとめ

サンゴのオプシンには,他の動物のオプシンとは異なり,クロライドイオンがカウンターイオンとして利用されます. 特定の残留物であるGlu292は,オプシンを安定させる上で二重の役割を果たします.

キーワード:
GPCR について生化学化学生物学サンゴカウンテリオン分子生物物理学オプシンスペクトロスコーピー構造生物学

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