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セトキシマブ- IR700 結合剤による光免疫療法による間接性肺炎

Yu Suekata¹, Tomoyuki Otsuka², Takuya Asai¹

¹Department of Head and Neck Surgery, Osaka International Cancer Institute, 3-1-69, Otemae, Chuo-ku, Osaka, 541-8567, Japan.

Auris, nasus, larynx

|September 1, 2025

まとめ

セトキシマブ- IR700 を用いたがん治療である光免疫療法 (PIT) は,インタースティシャル肺炎を引き起こす可能性があります. この症例報告は患者の詳細です

科学分野:

腫瘍学
免疫療法
薬理学について

背景:

光免疫療法 (PIT) は,がん治療に IR700 と結合したセトキシマブを使用します.
現在,日本では特定の頭頸部がんの治療に承認されています.
PITの臨床安全性に関するデータは限られている.

キーワード:

セトキシマブ-IR700結合体頭頸部がんインタースティシャル肺炎光免疫療法

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Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.