切除不能の局所的に進行した胆管がん (ZSAB- TransGOLP) でのチセリズマブとレンバチニブとGEMOXの変換療法: 多センター,前向きの第2相試験

Guoming Shi1, Xiaoyong Huang2, Xiaowu Li3

  • 1Department of Hepatobiliary Surgery and Liver Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China; Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, China; The Longevity and Aging Institute of Fudan University, Shanghai, China.

The Lancet. Oncology
|September 1, 2025
PubMed
まとめ

GOLP療法は,ティスレリズマブ,レンバチニブ,およびGEMOX化学療法を組み合わせ,切除不能の胆道がんを手術可能な疾患に変換し,管理可能な安全性で63%のR0切除率を達成することを約束しています.

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