関連する実験動画

Updated: Sep 9, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
11:34

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

Published on: May 10, 2022

2.3K

新型合成胆酸派生体は,同輸送ポリペプチドであるタウロコラートナトリウムのオリゴメリゼーションを妨害することで,B型肝炎ウイルス感染を侵入段階で抑制する

Gede Ngurah Rsi Suwardana1, Takayuki Abe2, Lin Deng3

  • 1Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan; Department of Microbiology, Faculty of Medicine, Udayana University, Bali, Indonesia.

Antiviral research
|September 1, 2025
PubMed
まとめ

新しい化合物であるSO-145は,肝臓細胞へのウイルスの侵入を阻害することで,B型肝炎ウイルス (HBV) 感染症の治療に有望であることが示されています. この新薬はHBVとD型肝炎ウイルスを阻害し,機能的な治療のための新たな戦略を提供している.

キーワード:
抗HBV剤胆酸派生体B型肝炎ウイルスNTCP についてナノルック

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