関連する実験動画
Updated: May 5, 2026

12:21
Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
Published on: September 12, 2011
25.3K
健康な新生児の脳接続の方向性と神経発達の結果
Venkata Chaitanya Chirumamilla1, Sarah B Mulkey2, Tayyba Anwar3
1The Zickler Family Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, United States.
Neuroscience letters
|September 1, 2025
まとめ
新生児の脳ハブ情報の流れは 認知,言語,運動の発達を予測します 早期の脳接続パターンは 電気脳波 (EEG) で測定され 2歳までの神経発達の結果と関連しています
科学分野:
- 神経科学
- 発達神経科学
- 小児神経学
背景:
- 早期の脳の発達は 長期的な神経発達に不可欠です
- 早期の脳活動と 後の発達との関係を理解することで 介入を促すことができます
- ニューラルネットワークの機能の重要な構成要素です ニューラルネットワークの機能の重要な構成要素です
研究 の 目的:
- 健康な新生児の脳のハブ間の方向情報流と2歳の時の神経発達の結果との関連を調べる.
- 初期の脳の接続の特定のパターンが 認知,言語,運動の発達を予測するかどうかを判断する
主な方法:
- 新生児の出生後72時間以内に脳活動を記録するために,高密度電脳図 (EEG) が使用されました.
- 脳のハブからの指向された情報フローは,デルタ帯の部分指向されたコヒーレンスを使用して計算されました.
- 神経発達の結果は,ベイリー幼児発達スケール-III (BSID-III) を用いて2年後に評価され,相関を分析するために段階的な回帰が採用されました.
主要な成果:
- 左と右の桃体と右の尾状核からのエフェレントフローは 認知スコアと否定的に関連していました
- 左側から発するエフェレントの流れと認知スコアとの間に正の関連性が見られた.
- 右桃体からのエフェレントフローと言語スコアとの間に否定的な関連が観察され,脳幹からのエフェレントフローは運動スコアと正に相関していた.
結論:
- 生まれた時の特定の脳ハブからのエッフェラー出力は 2歳の時の神経発達の結果と有意に関連しています
- これらの発見は 後の発達経路を予測する上で 早期の脳の接続性の重要性を強調しています
関連する概念動画
Neurulation
40.2K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
40.2K
Neurogenesis and Regeneration of Nervous Tissue
2.1K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
2.1K
Spinal Cord: Cross-sectional Anatomy
5.7K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Gray Matter and its Components
Central to the gray matter is...
5.7K
Major Somatic Sensory Pathways
3.2K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
3.2K
Neuroplasticity
2.6K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
2.6K
Gut-Brain Axis
222
The gut–brain axis is a bidirectional communication system that connects the gastrointestinal tract and the brain. This interaction is mediated through multiple pathways, including the vagus nerve, hormonal signals, immune responses, and chemical messengers produced by gut microbes.Microbial Contributions to Brain FunctionGut microbiota contributes significantly to brain function by producing neuroactive compounds. These include neuroactive compounds that influence neurotransmitters such...
222

