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Improving Translational Accuracy02:07

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Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
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骨科におけるモデル (機械学習を含む) の強度と解釈可能性の向上

Baptiste Boukebous1, Jacques-Emmanuel Galimard2, David Biau3

  • 1AP-HP - Orthopédie et Traumatologie, Hôpital Beaujon 100 Bd du Général Leclerc, Clichy 92110, France; Université Paris Cité, Paris, France.

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PubMed
まとめ

No abstract available in PubMed .

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