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Updated: Sep 9, 2025

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy
07:20

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy

Published on: January 31, 2025

650

TEAD1のデパルミトイライションは,PP2Acαをトランスアクティブ化することによって,脂質滴の蓄積と酸化ストレスに対する耐性を促進する

Xiaoli Sun1, Shuang Xu2, Yajie Ni2

  • 1Department of Clinical Genetics, 2nd Affiliated Hospital, Nanjing Medical University, 262 North Zhongshan Road, Nanjing, Jiangsu, China.

Free radical biology & medicine
|September 1, 2025
PubMed
まとめ

アセトアミノフェンの過剰投与は酸化ストレスを増やすことで肝不全を引き起こす. この研究は,TEAD1タンパク質が,脂質合成とドロップレット形成を通じて,遺伝子の発現を調節することによって,肝臓をこの損傷から保護することを明らかにしています.

キーワード:
急性肝不全デパルミトイライション海馬の経路液体と液体の相分離転写規制について

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