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Updated: May 7, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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アイソトープでコードされた空間生物学は,アルツハイマー病のマウスモデルにおけるプラーク年齢依存の成熟とシナプス喪失を特定する

Jack I Wood1,2, Maciej Dulewicz1,3, Alicja Szadziewska1

  • 1Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.

Nature communications
|September 1, 2025
PubMed
まとめ

アルツハイマー病の研究では 古いアミロイドβプラークはシナプス喪失と神経毒性に関連しています プラークの年齢を 追跡することで 病理が脳組織に どのように影響するかが 明らかになります 病状の全体的な段階とは無関係です

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