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Updated: Sep 9, 2025

Impedance-based Real-time Measurement of Cancer Cell Migration and Invasion
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毛細血管の収縮 PIEZO1による原発がん細胞腫瘍発生性

Giulia Silvani1, Chantal Kopecky2, Sara Romanazzo2

  • 1School of Materials Science and Engineering, UNSW, Sydney, NSW, Australia.

Nature communications
|September 1, 2025
PubMed
まとめ

狭い毛細血管を通して 循環するメラノーマ細胞を 物理的に圧迫すると 腫瘍発生性で 癌の幹細胞のような状態に 再プログラムされます PIEZO1によって媒介されるこの機械的ストレスは,転移の可能性と二次腫瘍を形成する能力を高めます.

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