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マグネシウム欠乏度と膀活動過剰との関連 NHANES 2005年から2018年までのデータを利用する成人の割合
Hege Bian1, Yuzhong Zhang1, Kun Liu2
1Supply Chain Department, Hefei BOE Hospital, Hefei, Anhui, 230013, China.
Scientific reports
|September 1, 2025
まとめ
マグネシウムの減少は,米国成人における過活動性膀 (OAB) 症状の高リスクと関連しています. この研究では,特に女性や肥満患者では,OABの確率が高く,マグネシウム欠乏のスコアが高くなりました.
科学分野:
- 泌尿器科
- 栄養学
- 公衆衛生
背景:
- 膀の活動過多は生活の質に重大な影響を及ぼします.
- マグネシウムは筋肉と神経の機能に重要な役割を果たし,膀のコントロールに影響を与える可能性があります.
研究 の 目的:
- マグネシウム欠乏症とOAB症状の関連性を調査する
- 低マグネシウムのレベルがOABの罹患率や重症度の上昇と相関するかどうかを判断する.
主な方法:
- NHANES 2005-2018からの28,621人の米国成人 (20〜80歳) のデータを分析した.
- マグネシウム減少スコア (MgDS) を用いたアンケートとマグネシウム減少スコアによるOAB症状の評価
- MgDSとOABリスクの関連性を評価するために,共変数に調整されたロジスティック回帰モデル.
主要な成果:
- より高いMgDSは,OABの確率の増加と有意に関連していました.
- MgDSの1ポイントの上昇は,OABの確率の9%の上昇と相関していた (OR=1. 09).
- 平均と高MgDS群の個人はそれぞれ17%と20%OABの確率を示しました. この関連性は女性,非喫煙者,中年,肥満者においてより強く見られた.
結論:
- マグネシウムの減少は,米国の成人の膀過剰症候群のリスクが高いと関連しています.
- この発見は,栄養状態と膀機能障害の間の潜在的な関連を強調しています.
- 原因関係を確立し,介入戦略を模索するために,さらなる研究が必要である.
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