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Updated: Sep 9, 2025

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
09:45

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

Published on: March 31, 2015

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Pentagamavunone-1は,ミトス停止によって媒介される過剰なMYCN/NCYM発現を標的とし,肝細胞がんの増殖を抑制する

Dhania Novitasari1,2,3, Ikuko Nakamae1, Noriko Yoneda-Kato1

  • 1Laboratory of Tumor Cell Biology, Institute for Research Initiatives, Nara Institute of Science and Technology, Nara, Japan.

Cancer gene therapy
|September 1, 2025
PubMed
まとめ

ペントガマヴノン-1 (PGV-1) は,細胞循環停止と衰老を誘導することによって,肝細胞癌 (HCC) 細胞の成長を効果的に抑制する. このカルキュミンの類型は,MYCN過剰発現の肝がんの標的治療として有望である.

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Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics06:00

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