母親のビタミンD摂取量は,母親と帯の血清25-ヒドロキシビタミンD,インタールイキン6,フェリチンと相関する
Yusrawati Yusrawati1, Efrida Efrida2, Nasrum Massi3
1Fetomaternal Division, Obstetrics and Gynecology Departement, Medical Faculty of Andalas University, Padang, West Sumatera, Indonesia. yusrawati_65@yahoo.co.id.
Scientific reports
|September 1, 2025
まとめ
母親のビタミンD摂取量は,母親と新生児の25-ヒドロキシビタミンD濃度と中程度の相関を示した. しかし,インタールイキン-6 (IL- 6) とフェリチンとの相関は弱かった.
科学分野:
- 産婦人科
- 栄養学
- 免疫学
背景:
- ビタミンDは胎児の発達,母親の免疫機能,胎盤の調節に不可欠です.
- ビタミンDの摂取量と 重要なバイオマーカーの関係を理解することは 母親と乳児の健康に不可欠です
研究 の 目的:
- 母親のビタミンD摂取量と25-ヒドロキシビタミンD (25~OH) D),インタールイキン-6 (IL-6),フェリチン の血清濃度との相関を調査する.
主な方法:
- 40人の妊婦を対象とした横断的な研究です
- 食品の頻度に関するアンケートと血清分析 (ELISA) で25...OH) D,IL-6,フェリチンについて収集したデータ.
- 正常分布のデータに適用されたピアソン相関テスト.
主要な成果:
- ビタミンDの摂取と母体/帯血清の25...OH) D濃度 (p < 0.016) の間には適度な相関が認められた.
- ビタミンDの摂取量と母体/帯のIL-6濃度との間に,弱い,有意な相関が観察された.
- ビタミンDの摂取量と母体/帯フェリチン濃度との間には,軽微な相関が認められた.
結論:
- 母親のビタミンD摂取は,母親と新生児の両方の血清25~OH) D濃度と適度に関連しています.
- ビタミンDの摂取はIL-6とフェリチンレベルとの弱い関連を示し,このコホートにおけるこれらの特定の炎症と鉄マーカーの影響が限られていることを示唆しています.
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