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Updated: Sep 9, 2025

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臓器選択的なmRNA配送のためのペプチドコード

Tie Chang1, Yifan Zheng1, Mingrui Jiang2

  • 1Institute of Biomechanics and Medical Engineering, Applied Mechanics Laboratory, Department of Engineering Mechanics, Tsinghua University, Beijing, China.

Nature materials
|September 1, 2025
PubMed
まとめ

研究者は,ペプチドでコードされた臓器選択標的 (POST) 方法を開発し,伝達 RNA (mRNA) を肝臓以外の臓器に届けました. この新しいLNPエンジニアリングアプローチは,潜在的な遺伝子治療のための肝臓外mRNA配送を強化します.

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