世界的な臓炎の負担と社会経済的格差 (1990-2021) の包括的な年齢期対コホート分析
Wei Liu1, Zhenguo Qiao2, Chao Du3
1Department of Minimally Invasive Common Surgery, Suzhou Ninth People's Hospital, Xuzhou Medical University Suzhou Bay Clinical College, Suzhou, Jiangsu Province, China.
BMC gastroenterology
|September 1, 2025
まとめ
炎の発生率と死亡率は世界的に増加しており,社会人口指数 (SDI) が低い地域を不釣り合いに影響しています. 高度なアルコール消費は重要なリスク因子であり,脆弱な地域における標的型介入と医療へのアクセスの改善の必要性を強調しています.
科学分野:
- 世界保健疫学
- 疾病負担の分析
- 公衆衛生政策
背景:
- パンクレアチスは,発生率の増加,複雑な管理要件,および実質的な死亡率によって特徴づけられる,重要で増大する世界的な健康問題です.
- この研究では,年齢,期間,出生コホート,社会人口指数 (SDI) を含む人口統計学的要因が,全世界の炎の負担に及ぼす影響を調査しています.
- 高度なアルコール摂取は 炎の全体的な負担に寄与する 重要な危険因子として特定されています
研究 の 目的:
- 1990年から2021年までのパンクレアチス発生率,死亡率,障害調整寿命 (DALYs) の世界的な傾向と格差を分析する.
- 年齢,月経,出生コホート,およびSDIが,世界各地域および国における炎の負担に及ぼす影響を調査する.
- 高度なアルコール使用が臓炎による死亡率に与える影響を評価し,性別の傾向を調べる.
主な方法:
- 2021年グローバル・バーデン・オブ・ディジーズ (GBD) 研究のデータを利用し,包括的な分析を行いました.
- 炎の発生率,死亡率,およびDALYの動向を分析するために,年齢期間コホート (APC) モデルを使用した.
- 高いアルコール消費量に関連した健康格差を調査するために,SDIによって国をグループ化し,ベイジアンメタリグレッションを実施しました.
主要な成果:
- 全世界の臓炎患者は1990年から2021年の間に173万人から275万人,死亡者は68,490人から122,416人,DALYは258人から410万人へと増加しました.
- 高度なアルコール使用は,約16%の炎による死亡に起因し,男性に不釣り合いな影響を及ぼしました.
- SDIが低い地域と SDIが低い地域では 臓炎の負担が増加し,SDIが高い地域では減少しており,これは医療の格差を示しています. 東欧はアルコール消費による負担が最も高く,高所得のアジア太平洋地域は最も低い割合を示しています.
結論:
- パンクレアチスは依然として重要な世界的な健康問題であり,地域格差が大きく,特にSDIが低い地域に影響を与えています.
- 高いSDI地域における効果的な政治行動が負担を軽減した一方で,低いSDI地域では課題が拡大しています.
- 高いアルコール使用量に対処し,SDIの低い地域での医療を強化し,監視を改善し,病気の理解を深めることは,将来の介入に不可欠です.
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