高い体量指数と予測傾向による甲状腺がんの世界的負担:世界保健データ研究 (1990-2021) の推定結果
Xinjun Zhang1, Hua Fan2, Qingwen Yu3
1Department of Thyroid and Breast Surgery, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, 310015, Zhejiang Province, China.
Thyroid research
|September 2, 2025
まとめ
体重指数 (BMI) が高くなると 甲状腺がんが世界的に増加します 体重管理は この一般的な内分泌腫瘍を 予防するのに役立ちます 特に社会経済的に低い地域では
科学分野:
- 内分泌学
- 腫瘍学
- 公衆衛生
背景:
- 甲状腺がんは最も一般的な内分泌腫瘍で 生活の質と社会的な課題を 引き起こしています
- 体重指数 (BMI) が高くなることは,世界的に懸念される問題です.
- 高体量指数と 甲状腺がんの負担の関係を理解することは 公衆衛生戦略にとって極めて重要です
研究 の 目的:
- 過去30年間,高体量指数 (BMI) に起因する甲状腺がんの世界的な負担を推定する.
- 高体量指数に関連する甲状腺癌の時間的傾向と地域的格差を分析する.
- 甲状腺がんの負荷の将来の傾向を予測し,予防の取り組みを伝える.
主な方法:
- 高体量指数に関連した甲状腺がんの抽出死亡率,障害調整寿命年数 (DALYs),および年齢標準化率 (ASRs).
- トレンド分析のためのASRの推定年間パーセント変化 (EAPC) を計算するために一般化された線形モデルを使用した.
- 社会開発指数 (SDI) とDALY率との関連を評価するためのSpearmanのランク相関と,将来の予測のためのベイジアン年齢期間コホート (BAPC) モデル.
主要な成果:
- 甲状腺がんの世界的なDALYは1. 49 (1990) から1. 68 (2021) に増加し,EAPCは0. 377で,上昇傾向を示しています.
- 127カ国のSDIは増加傾向を示し,特にSDIが低い地域と中程度の地域では減少傾向を示した.
- 甲状腺がんの負担 (DALYsとASDR) は女性より高く,2020年から2035年まで世界中で増加すると予測されています.
結論:
- 高いボディマス指数は 甲状腺がんの世界的な負担と 大きく関連しています
- 総合的な体重管理戦略は 甲状腺がんの発症を緩和したり予防したりする上で 重要な役割を果たすかもしれません
- この研究は,将来の甲状腺がんの予防と制御のための貴重なデータを提供し,高体量指数に対処することの重要性を強調しています.
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