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Updated: Sep 9, 2025

Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts
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Published on: August 1, 2025

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プロリン代謝における重要な酵素PYCR1:癌の進行と線維性再構成の二重の原動力

Peng Guo1,2, Chenchun Wu3, Tong Wang1

  • 1Department of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Journal of enzyme inhibition and medicinal chemistry
|September 2, 2025
PubMed
まとめ

ピロリン5カルボキシラート還元酵素1 (PYCR1) はプロリン合成に不可欠であり,カティスラクサに関連しています. PYCR1阻害剤は 代謝変化によって癌と線維症を誘発しますが PYCR1阻害剤は 臨床検証が必要です

キーワード:
PYCR1 について癌について繊維症代謝の再プログラムプロリン代謝

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