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Updated: Sep 9, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

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2,6-ディアザビサイクロ[3.3.1]ノナンの合成

Ryosuke Kawai1, Asano Nakamura1, Yui Irie1

  • 1Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya 464-8601, Japan. yokoshima.satoshi.v7@f.mail.nagoya-u.ac.jp.

Organic & biomolecular chemistry
|September 2, 2025
PubMed
まとめ

新しい合成法により,構造的に制限されたダイアミンのための価値ある支架である2,6-ディアザビサイクロ[3.3.1]ノナンが生成される. この経路では,容易に入手できるピペリジン誘導体と,効率的な骨格構造のための分子内サイクル添加を使用します.

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