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Updated: Sep 9, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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新しいイミダゾリノンの脊髄キラルN,Pリガンドの設計と製造と,その高度な有効性によるエナンチオセレクティブアリレーション

Guo Cheng1,2, Sen Lu1,2, Jing-Liang Yu1,2

  • 1Key Laboratory of Asymmetric Synthesis and Chirotechnology of Si-chuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China. wlxioc@cioc.ac.cn.

Organic & biomolecular chemistry
|September 2, 2025
PubMed
まとめ

マックミラン有機触媒とN,P-リガンドを組み合わせた新しいキラルリガンドが合成されました. これらのリガンドは,パラジウム触媒によるアリレーション反応において高いエナチオ選択性を達成し,非対称合成への新しいアプローチを提供します.

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