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Updated: Sep 9, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

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カスタノスペルミンに類似するポリヒドロキシル化3メチルインドリジジドンの合成のためのドミノ・グリナード添加/コップ・ハウスの反応

Thomas Lulli1, Filippo Dei1, Macarena Martínez-Bailén1

  • 1Dipartimento di Chimica 'Ugo Schiff' (DICUS), Università di Firenze, via della Lastruccia 3-13, 50019 Sesto Fiorentino (FI), Italy.

Organic letters
|September 2, 2025
PubMed
まとめ

研究者らは,ポリヒドロキシル化3メチルインドリジディンの最初の合成を報告した. この効率的な3〜4段階の方法はドミノ反応を用いて,貴重なバイサイクル化合物へのアクセスを提供します.

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