マキシロマンディブル・アドバンス後の持続的なOSA:薬剤誘発睡眠内視鏡からの洞察
1Department of Head and Neck Surgery, University of California, Los Angeles, Los Angeles, California, USA.
まとめ
薬剤誘発性睡眠内視鏡検査では,マキシロマンジブラー進出 (MMA) の後に続く阻害性睡眠無呼吸症候群 (OSA) が,しばしば舌の阻害を含んでいる. 前回の手術のない患者と比較して,MMA後の先頭葉の阻害はより頻繁です.
科学分野:
- 耳鼻喉科
- 睡眠医学
- 手術 の 結果
背景:
- 阻害性睡眠無呼吸 (OSA) は,睡眠中に再発的な上部呼吸道崩壊を特徴とする一般的な状態です.
- マキシロマンディブーラ・アドバンスメント (MMA) は,上下の位置を変えることでOSAを治療する手術である.
- MMA後の持続的なOSAは,残留呼吸道阻害パターンのさらなる調査を必要とします.
研究 の 目的:
- MMA後の持続的なOSA患者の上部呼吸道阻害パターンを薬剤誘発性睡眠内視鏡 (DISE) を使用して評価する.
- 特定の阻害部位 (舌,毛皮,頭蓋骨,側壁) をVOTE分類を用いて特徴づけること.
主な方法:
- 学術医療センターで横断的な研究が行われました.
- 薬剤誘発性睡眠内視鏡検査 (DISE) は,プロポフォール鎮静剤を投与した24人の成人患者に実施し,MMA投与後,手術後のアプネア・ヒポネア指数 (AHI) が≥5であった.
- 呼吸道阻害パターンは,VOTE (頭蓋骨,口腔,舌,頭蓋骨) システムを用いて,横になった状態で分類された.
主要な成果:
- 24人の患者がDISEを受け,平均年齢は46. 4歳,女性の割合は12%でした. MMA後の平均時間は889日であり,MMA後のAHIは18. 2事件でした.
- DISEでは,舌による阻害が最も頻繁に見られました.
- 前回の喉手術のないコホートと比較して,MMA後の患者は,ベラムと喉側壁の阻害が少なく,エピグロティスに関連する阻害が多く示されました.
結論:
- MMA後の持続的なOSA患者の上部呼吸道阻害は,複数の解剖学的部位を伴う.
- 舌による阻害は一般的であり,先行した喉手術のない人と比較して,MMA後の喉関連の阻害はより一般的です.
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