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Updated: Sep 9, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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オプトレギュレーションされたmRNA配送は,腫瘍標的治療のためのプレオトロプ免疫シグナリングを制御する

Pengwen Chen1, Guanghao Hu1, Yuki Nakashima1

  • 1Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Angewandte Chemie (International ed. in English)
|September 2, 2025
PubMed
まとめ

新しい光誘発伝染システム (LITS) は,メッセンジャーRNA (mRNA) 治療法を正確に制御することができます. このシステムは,腫瘍における標的型タンパク質発現を可能にし,より安全な治療のために毒性を最小限に抑えながら,抗腫瘍活動を強化します.

キーワード:
エンドソーム脱出免疫療法インタールイウキン-2メッセンジャーRNA光感受剤

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