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Updated: Sep 9, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

1.2K

偽狂犬病ウイルスは,TfR1とフェリチノファギーの活性化によって鉄の恒常性を乱すことでフェロプトーシスを誘発する

Zicheng Ma1, Lei Guo1, Ran Ji2

  • 1Key Laboratory of Animal Diseases Diagnostic and Immunology, Ministry of Agriculture, MOE International Joint Collaborative Research Laboratory for Animal Health & Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.

Journal of virology
|September 2, 2025
PubMed
まとめ

偽熱ウイルス (PRV) の感染は,鉄過量に依存する細胞死経路であるフェロプトーシスを引き起こす. PRVはトランスファーリン受容体1とフェリチノファギーを利用して細胞内鉄を増やし,ウイルスの複製を促進します.

キーワード:
PRV についてTfR1 についてフェリチノファジーフェロプトーシス鉄 ホメオスタシスプログラムされた細胞死

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Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining07:32

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