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Updated: Sep 9, 2025

Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster
06:45

Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster

Published on: November 21, 2018

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ネットワーク毒理学と分子ドッキングによって研究されたピレトロイドの神経毒性メカニズム

Yuting Lin1, Wenqi Zeng1, Yang Zhang1

  • 1Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, The First Dongguan Affiliated Hospital, School of Basic Medical Sciences, Guangdong Medical University, Dongguan, China.

Toxicology mechanisms and methods
|September 2, 2025
PubMed
まとめ

ピレトロイド (PYs) は,重要なタンパク質標的とシグナル伝達経路に影響を与えることで神経毒性を引き起こします. この研究では,SRCとEGFRのような主要な標的が特定され,PYsによる神経損傷の潜在的なメカニズムが明らかになりました.

キーワード:
AGE-RAGE信号経路についてピレトロイド分子ドッキングネットワーク毒性神経毒性

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Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing09:02

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