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Updated: Sep 9, 2025

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アッシャー症候群に関与するUSH1G遺伝子の有害なミスセンスのSNPの計算研究

Kenza El Khair1,2, Madoussou Toure1, Salaheddine Redouane1

  • 1Genomics and Human Genetics Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.

Journal of biomolecular structure & dynamics
|September 2, 2025
PubMed
まとめ

この研究では,Usher症候群に不可欠なUSH1G遺伝子の5つのインパクトのあるミスセンスのSNPを計算的に特定しました. これらの変異はSANSタンパク質の安定性と動態を大幅に変化させ,遺伝状態の洞察を提供します.

キーワード:
計算によるアプローチUSH1G分子ダイナミクスシミュレーションnsSNP について統計分析

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