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Updated: Sep 9, 2025

A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
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Published on: March 17, 2015

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タイプIインターフェロンは,ヒトの背根のガンジオン受容体の興奮性を高め,TRPV1の感受性を誘発する

Úrzula Franco-Enzástiga1, Keerthana Natarajan1, Felipe Espinosa1

  • 1Department of Neuroscience, University of Texas at Dallas, Dallas, United States of America.

JCI insight
|September 2, 2025
PubMed
まとめ

タイプIインターフェロン (IFN) は人間の感覚神経細胞を活性化し,痛みを引き起こします. eFT508で特定のキナーゼ (MNK1/ 2) を阻害すると,このIFN誘発のニューロンの過興奮性と痛みの感受性を阻害する.

キーワード:
炎症神経科学痛みを感じる

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