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Updated: Sep 9, 2025

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
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メタボローム・ワイド・メンデルのランダム化により,バリンが臓がんリスクに対する肥満の影響を媒介する可能性があることが判明した

Kui Li1, Chao Zhang2, Cheng Yan2

  • 1Department of Pharmacy, Xinxiang Central Hospital, Xinxiang, China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|September 2, 2025
PubMed
まとめ

肥満は臓がん (PC) のリスクを高めますが,そのメカニズムは不明です. この研究では,その代謝物であるバリンが,肥満とPCを因果的に結びつけ,そのリスクを部分的に媒介していることが判明した. 肥満に起因する臓がんの 重要な要因として 強調しています

キーワード:
メンデルのランダム化メタボライト肥満臓がんバリン濃度

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