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Updated: Sep 9, 2025

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
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Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis

Published on: March 30, 2019

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circHMGCS1 HuR/SFPQ/TNF経路を調節することでNSCLCの進行を促進する

Jiayue An1,2, Weimiao Sun1,2, Chenhui Ti1,2

  • 1The Second Medical College of Binzhou Medical University, Yantai, Shandong, People's Republic of China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|September 2, 2025
PubMed
まとめ

新種の循環型RNAであるcircHMGCS1は,非小細胞肺がん (NSCLC) で上位調節される. 腫瘍性HuRタンパク質を安定させ,SFPQ mRNAのアップレギュレーションとNSCLCの進行を促進し,診断用バイオマーカーとしての可能性を示唆しています.

キーワード:
HUR についてNSCLC についてSFPQ についてサークルRNAsどこにでもいる

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