都市教育病院の産前診療所での自己採取の陰道サンプルによる一次性子宮頸部スクリーニングの許容性,安全性,および性能
Su Pei Khoo1, Joanne Johnny Bouniu1, Lavanya Sivaram1
1Department of Obstetrics and Gynaecology, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
PLOS global public health
|September 2, 2025
まとめ
マレーシアでは,ヒトパピロマウイルス (HPV) 検査のために自己採取した陰道サンプルが実行可能で安全で,妊娠中の女性にとって非常に許容される. このアプローチは検診不足の集団における 子宮頸がんの検診率を向上させることができます
科学分野:
- 婦人科と産婦人科
- 感染症
- 公衆衛生
背景:
- 子宮頸がんのスクリーニングは 早期発見と予防に不可欠です
- ヒトパピローマウイルス (HPV) 検査は,主要なスクリーニング方法です.
- 検診を産前ケアに組み込むことで 検診不足の妊婦群に届くことができます
研究 の 目的:
- 妊婦のHPV検査のための自己採取の検体の可行性,安全性,受容性を評価する.
- 標準的な方法と比較して自己採集のパフォーマンスを評価する.
- 子宮頸がんのスクリーニングの吸収を高めるための自己採集の可能性を決定する.
主な方法:
- マレーシアの都市にある教育病院で30歳以上の妊婦を対象とした横断的な研究.
- 参加者はFLOQSwabを使って自己採取したのサンプルを採取した.
- 試料は,受容性を評価するアンケートを使用して,ロシェコバス4800システムを用いてHPVを分析した.
主要な成果:
- 高い吸収率 (71.1%) と自己採集の完了率 (98. 6%) が観察されました.
- 参加者の80%以上は,好ましい受け入れの指標 (容易さ,便利さ,信頼) を報告した.
- HPVの罹患率は6. 3%で,重大な合併症は報告されていません. 99.0%が将来の自己回収の意思を表明した.
結論:
- HPV検査のために自己採取した陰道サンプルは,妊娠中の女性にとって安全で,実行可能で,非常に許容可能な方法です.
- このアプローチは,一般の人々と比較可能なパフォーマンスを示しています.
- 自己採集を産前ケアに統合することで 子宮頸がんのスクリーニング率を大幅に改善し,世界的な排除の取り組みを支援することができます.
関連する概念動画
Assessment of the Rectum and Anus
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
Urologic Endoscopic Procedure: Cystoscopic Examination
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
Urine Studies II: Urine Culture and Sensitivity Test
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...


