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Updated: Sep 9, 2025

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
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ヒトパピローマウイルスゲノムは,持続的なウイルス感染中に主体クロマチンと結合する

Alix Warburton1, Tovah E Markowitz2, J J L Miranda3

  • 1Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

PLoS pathogens
|September 2, 2025
PubMed
まとめ

ヒトパピローマウイルス (HPV) のゲノムは,宿主細胞の活性クロマチン領域と関連しています. この関連性はウイルスの遺伝子発現を促進しますが,DNAの破損に対する感受性を高め,がんにおけるHPV統合を潜在的に説明します.

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