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Updated: Sep 9, 2025

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ケロイド病を阻害するBAG2に高い afinityを持つ化合物の治療的可能性

Yinmin Wang1, Zhaoqi Yuan1, Renpeng Zhou1

  • 1Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, People's Republic of China.

Biologics : targets & therapy
|September 2, 2025
PubMed
まとめ

この研究では,Bcl-2-関連アタノゲン2 (BAG2) がケロイド病理学の重要な役割を果たしていることが判明しました. バゼドキシフェンアセテートとポネシモドは,BAG2を阻害する標的化ケロイド治療として有望である.

キーワード:
BAG2 についてバゼドキシフェンアセテートケロイド表面プラズモンの共鳴ターゲティング療法

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