中国温州市における移住者集団における耐薬性結核の流行と流行病学的パターン, 2014-2023年:公衆衛生戦略への影響
Lianpeng Wu1,2, Xiyue Cai3, Shuya Xu4
1Department of Clinical Laboratory Medicine, The Ding Li Clinical College of Wenzhou Medical University, Wenzhou Central Hospital, Wenzhou, China.
Frontiers in public health
|September 2, 2025
まとめ
多剤耐性結核 (MDR-TB) の報告は2014年から2023年の間に中国温州市で減少した. 移住者はMDR-TB症例のほぼ半分を占め,標的型公衆衛生介入の必要性を強調しています.
科学分野:
- 流行病学
- 感染症
- 公衆衛生
背景:
- 多剤耐性結核 (MDR-TB) が特に脅威となっている.
- 多剤耐性結核 (MDR-TB) の流行病学的パターンの理解は,特に多様な集団において,効果的な制御戦略にとって極めて重要です.
研究 の 目的:
- 2014年から2023年の間に中国温州市で報告されたMDR-TB症例の疫学的特徴と時間的傾向を分析する.
- 温州市内の移民と地元住民の間でMDR-TBの流行の違いを調査する.
主な方法:
- 結核情報管理システム (TBIMS) と病院の検査記録から得られたデータを利用した施設ベースの遡及コホート研究.
- 含有基準: 細菌学的に確定した結核の症例と,現行のフェノタイプ薬感性検査 (pDST) の結果.
- 統計的分析には,ピアソンのチ平方テスト,トレンドチ平方テスト,および人口と分布の分析のためのサンキー図が含まれていました.
主要な成果:
- 報告された10993人の結核患者のうち734人 (6. 68%) がMDR- TBと診断された.
- 報告された症例のMDR- TBの割合は,研究期間中に著しく減少した (p < 0. 001).
- 移住者はMDR-TB症例の47.96% (352/734) を占め,その多くは江省内外から発生した.
結論:
- 温州市におけるMDR-TB報告の発生率は減少傾向にある.
- 移民集団はMDR-TB症例の 相当な割合を占めており 集中的な公衆衛生介入が必要である.
- MDR-TBの感染をさらに減らすためには,移民集団に対する監視と標的型介入を優先することが不可欠です.
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