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Updated: Sep 9, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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ロヒトゥキンとディゾリンと,その抗がん類のフラボピリドールとIIIM-290の総合成

Madhusmita Nayak1,2, Kailas V Kallurkar1,2, Tejaswi Somarowthu1,2

  • 1Department of Natural Products & Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad, Telangana 500007, India.

ACS omega
|September 2, 2025
PubMed
まとめ

この研究は,ロヒトゥキンとその類似体の重要なキラル中間物質の効率的な非対称合成を示し,フラボピリドールのような強力なCDK9/T1阻害剤のスケーラブルな生産を可能にします.

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