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Updated: Sep 9, 2025

Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes
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Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes

Published on: July 28, 2018

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エナチオセレクティブ Pd-カタライズされた核性C ((sp3) -H (放射性) 化

Nikita Chekshin1, Luo-Yan Liu1, D Quang Phan1

  • 1Department of Chemistry, The Scripps Research Institute; 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Nature catalysis
|September 2, 2025
PubMed
まとめ

研究者は,アミドとラクタムのエナチオセレクティブC-H化のための新しいパラジウム触媒方法を開発した. この画期的な発見により 価値あるキラル・フッ素化合物の合成が可能になり 薬物の発見のための18F放射性マーキングが容易になりました

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