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Updated: Sep 9, 2025

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes

Published on: September 15, 2018

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IMM- H007は,AMPKαを活性化させ,高コレステロール血症を緩和することによって,肝臓のコレステロールとトリグリセリド代謝を促進する

Jiaqi Li1, Mingchao Wang2, Kai Qu2

  • 1Department of Cardiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.

Acta pharmaceutica Sinica. B
|September 2, 2025
PubMed
まとめ

AMPKアゴニストであるIMM- H007は,高コレステロール血症におけるコレステロールとトリグリセリド代謝を改善する. 肝臓のコレステロールの吸収と胆酸の変換を高め 脂肪肝を予防します

キーワード:
AMPK について動脈硬化症コレステロールFXR について高コレステロール血症IMM-H007 についてLDLR についてトリグリセリド

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