1990年から2021年までの中国における胆囊および胆道疾患の負担とリスク要因,および今後15年間のリスク要因の負担予測
Shijun Zhao1, Yan Zhou1, Wangyou Tang2
1Department of General Surgery, The Second Hospital of Shandong University, Jinan, Shandong, China.
Frontiers in medicine
|September 2, 2025
まとめ
中国における胆囊および胆道疾患 (GBDT) は,1990年から2021年の間に発生率と流行率が変動した. 高体量指数 (HBMI) は,GBDTの負担に大きく寄与し,予測では障害が増加するが,死亡率は低下している.
科学分野:
- 疫学と公衆衛生
- 消化器系 の 病気
- 世界保健指標
背景:
- 胆囊と胆道疾患 (GBDT) は,中国では一般的な,しかし十分に記録されていない消化器系疾患です.
- 中国の人口におけるGBDTに関する包括的な疫学的なデータは限られている.
- GBDTの傾向を理解することは 公衆衛生の取り組みにとって極めて重要です
研究 の 目的:
- グローバル・バーデン・オブ・ディジーズ・スタディ2021のデータベースを用いて,1990年から2021年にかけての中国におけるGBDTの流行病的負担を分析する.
- GBDTの傾向と将来の予測,特に高体量指数 (HBMI) との関連を調査する.
- 年齢で標準化された発生率,罹患率,死亡率,障害調整寿命年数 (DALYs) を評価する.
主な方法:
- 全面的な疫学分析のために,Global Burden of Disease Study 2021のデータベースを利用した.
- 1990年から2021年までの疾病負担の動向を評価するJoinpointのリグレッション分析
- 死亡率とDALYを含む高体量指数 (HBMI) に関するGBDTの傾向を分析し,15年予測した.
主要な成果:
- 中国における胆囊および胆道疾患 (GBDT) の流行および発生率は1990年から2021年の間に変動し,世界的な幅度は減少傾向にある.
- GBDTの死亡率 (ASMR) と障害調整寿命年数 (ASDR) は低いままであり,ASDRは年々ゆっくりと減少している.
- 特に高体量指数 (HBMI) に関するGBDTの負担は,高齢者や女性に対して不釣り合いな影響を及ぼします.HBMIに関連したGBDTは,死亡率を下げながらDALYを増やすと予測されています.
結論:
- 胆管および胆道疾患 (GBDT) は,中国に重大な影響を及ぼす世界的な公衆衛生上の懸念事項であり続けています.
- 中国におけるGBDTの発生率と年齢標準化発生率 (ASIR) は1990年から2021年まで増加した.
- 高い体量指数 (HBMI) は,中国でGBDTの病気負担を増加させ,標的を絞った介入を必要とします.
関連する概念動画
01:26Diseases of the Liver and Gallbladder
965
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
965
01:17Gallbladder
896
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
896
01:16Hepatic Drug Excretion: Influencing Factors
214
The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
214
01:17Chronic Bowel Disorders: Introduction
540
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
540
01:24Chronic Pancreatitis I: Introduction
148
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
148
01:30Bulimia Nervosa
191
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
191